Sunday, August 12, 2018

Pharmacology MCQs- 120

A 52-year-old man diagnosed with gout is presented to his physician to discuss his treatment plan. One of the treatments that will be taken is allopurinol.

Which of these enzymes is targeted by allopurinol?

A-Hypoxanthine guanine phosphpribosyl transferase

B-Phosphoribosylpyrophosphate synthase


D-Xanthine oxidase


Treating gout with allopurinol lowers the production of uric acid in the body. Allopurinol is known to be an inhibitor of xanthine oxidase. Xanthine oxidase forms the metabolic pathway for the formation of uric acid. Due to this, xanthine oxidase inhibitor allopurinol is used in treating gout.

The correct answer is D

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