Saturday, August 18, 2018

Pharmacology MCQs- 121

A 66-year-old man is brought to the emergency room as he has been feeling palpitations and lightheadedness for the last 5-6 hours. The patient also states that he has experienced such episodes of palpitations earlier as well, but it did not last for so long and was not so severe either. Upon being admitted to the hospital, a complete cardiac workup is conducted. The patient is then diagnosed with rapid atrial fibrillation. Doctors suspect that this is also likely secondary to a moderately stenosed mitral valve as well. Doctors begin medical treatment for converting the patient to sinus rhythm, but it proves to be unsuccessful. The heart rate is brought under control with the use of several atrioventricular node blocking agents. Doctors prescribe daily medications that include drugs for controlling the potentially severe complications of atrial fibrillation.

Which of these would be the most likely prescribed drugs for long-term prevention of such complications in the patient?

A- Aspirin

B- Protamine sulfate

C- Streptokinase

D- Warfarin


Warfarin is a medication popularly prescribed to be used as an anticoagulant, meaning it prevents the formation of blood clots. Chronic atrial fibrillation increases the risk of systemic embolization and clot formation. The patient, therefore, needs to continue taking an anticoagulant to prevent complications such as mesenteric infarction or cerebrovascular accidents. Warfarin is the ideal medication in this case as it will inhibit any blood clots from forming.

The correct answer is D

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